MODERN VIEW ON THE PROBLEM OF TREATMENT OF INFECTIOUS PERITONITIS IN CATS
УДК: 619:579:636.8.045 DOI: 10.31588/2413_4201_1883_2_254_130
Keywords:
feline infectious peritonitis, FIP, etiotropic therapy, GS-441524, «Coronacat»Abstract
Feline infectious peritonitis (FIP) is a fatal immune-mediated viral disease of felines. Cats of all ages get sick, but young animals under the age of 2 years, as well as adults over 10 years old, are most sensitive. The prognosis for a cat with FIP is extremely poor - 99% fatal. This article presents a modern view on the problem of treating feline infectious peritonitis. A brief review of drugs proposed for symptomatic and etiotropic treatment of the disease is presented. From the review, it can be concluded that most of the drugs proposed for the etiotropic treatment of FIP have a weak evidence base and require further research. One of the most effective agents was the nucleoside analogue GS-441524, developed by Gilead Sciences. On the basis of GS-441524, a licensed preparation "Coronacat " was created (developer by VETUCHASTOK LLC, manufacturer - Promvetservice-Alba branch of Promvetservis LLC).
References
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Takano, T. Differential effects of viroporin inhibitors against feline infectious peritonitis virus serotypes I and II / T. Takano, K. Nakano, T. Doki, T. Hohdatsu // Arch Virol. -- 2015. -- No. 160(5). -- P. 1163-1170.
Takano, T. Antiviral Effects of Hydroxychloroquine and Type I Interferon on In Vitro Fatal Feline Coronavirus Infection / T. Takano, K. Satoh, T. Doki, T. Tanabe, T. Hohdatsu // Viruses. -- 2020. -- No. 12(5).
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