CONDITIONALITY OF PRODUCTIVE QUALITIES OF CATTLE OF THE REPUBLIC OF TATARSTAN BY OSTEOPONTIN GENE POLYMORPHISM

УДК: 636.034:636.082 DOI: 10.31588/2413_4201_1883_4_260_148

Authors

  • Mukhanina E.N. Tatar Research Institute of Agriculture of the Federal Research Center "Kazan Scientific Center of the Russian Academy of Sciences"
  • Safina N.Yu. Tatar Research Institute of Agriculture of the Federal Research Center "Kazan Scientific Center of the Russian Academy of Sciences"
  • Fattakhova Z.F. FSBEI HE "Kazan Bauman State Academy of Veterinary Medicine"
  • Gainutdinova E.R. Tatar Research Institute of Agriculture of the Federal Research Center "Kazan Scientific Center of the Russian Academy of Sciences"
  • Shakirov Sh.K. FSBEI HE "Kazan Bauman State Academy of Veterinary Medicine"
  • Ravilov R.Kh. FSBEI HE "Kazan Bauman State Academy of Veterinary Medicine"; Separate Structural Subdivision "Institute of Applied Research of the Academy of Sciences of the Republic of Tatarstan"

Keywords:

cattle, PCR-RFLP, polymorphism, osteopontin, OPN gene, secreted phosphoprotein, SPP1, reproduction

Abstract

The aim of the study was to study the polymorphism of the OPN gene (p.8514 C→T) in the population of Holstein cows of domestic breeding in the Republic of Tatarstan and its effect on economically significant traits. The longest dry period and the highest yield of calves per 100 cows were observed in individuals carrying the TT genotype of the OPN gene. The earliest age of the first fruitful insemination, the highest live weight, elongated service and interbody periods were observed in cows with the CC genotype of the OPN gene. In animals of this genotype, the highest percentage of milk yield was revealed – 8.9%, leading in the long term to high losses due to milk losses.

Author Biographies

Mukhanina E.N., Tatar Research Institute of Agriculture of the Federal Research Center "Kazan Scientific Center of the Russian Academy of Sciences"

Cand. Sci. (Biol.), Senior Researcher

Safina N.Yu., Tatar Research Institute of Agriculture of the Federal Research Center "Kazan Scientific Center of the Russian Academy of Sciences"

Cand. Sci. (Biol.), Senior Researcher

Fattakhova Z.F., FSBEI HE "Kazan Bauman State Academy of Veterinary Medicine"

Cand. Sci. (Biol.), Assistant

Gainutdinova E.R., Tatar Research Institute of Agriculture of the Federal Research Center "Kazan Scientific Center of the Russian Academy of Sciences"

Postgraduate Student, Researcher

Shakirov Sh.K., FSBEI HE "Kazan Bauman State Academy of Veterinary Medicine"

Dr. Sci. (Agric.), Professor, Chief Researcher

Ravilov R.Kh., FSBEI HE "Kazan Bauman State Academy of Veterinary Medicine"; Separate Structural Subdivision "Institute of Applied Research of the Academy of Sciences of the Republic of Tatarstan"

Dr. Sci. (Vet.), Professor

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Eberlein, A. Dissection of genetic factors modulating fetal growth in cattle indicates a substantial role of the non-smc condensin I complex, subunit G (NCAPG) gene / A. Eberlein, A. Takasuga, K. Setoguchi // Genetics. – 2009. – V. 183(3). – P. 951-964. – DOI: 10.1534/genetics.109.106476.

Franczyk, M. Extracellular matrix proteins in healthy and retained placentas, comparing hemochorial and synepitheliochorial placentas / M. Franczyk, M. Lopucki, N. Stachowicz [et al.] // Placenta. – 2017. – V. 50. – P. 19-24. – DOI: 10.1016/j.placenta.2016.12.014.

Johnson, G. A. Muc-1, integrin, and osteopontin expression during the implantation cascade in sheep / G. A. Johnson, F. W. Bazer, L. A. Jaeger [et al.] // Biology of Reproduction. – 2001. – V. 65. – P. 820-828. – DOI: 10.1095/biolreprod65.3.820.

Johnson, G. A. Osteopontin: a leading candidate adhesion molecule for implantation in pigs and sheep / G. A. Johnson, R. C. Burghardt, F. W. Bazer // J. Anim. Sci. Biotechnol. – 2014. – V. 5(1). – P. 56. – DOI: 10.1186/2049-1891-5-56.

Kao, L. C. Global gene profiling in human endometrium during the window of implantation / L. C. Kao, S. Tulac, S. Lobo [et al.] / Endocrinology. – 2002. – V. 143(6). – P. 2119-2138. – DOI: 10.1210/endo.143.6.8885.

Karthikeyan, A. Characterization and in-silico analysis of Osteopontin gene in vechur cattle of Kerala / A. Karthikeyan., G. Radhika, T. V. Aravindakshan // J. Entomol. Zool. Stud. – 2020. – V. 8 (2). – P. 262-266.

Kowalewska-Łuczak, I. Polymorphism of the FAM13A, ABCG2, OPN, LAP3, HCAP-G, PPARGC1A genes and somatic cell count of Jersey cows-preliminary study / I. Kowalewska-Łuczak, H. Kulig // Res. Vet. Sci. – 2013. – V. 94 (2). – P. 252-255. – DOI: 10.1016/j.rvsc.2012.08.006.

Leonard, S. Effects of the Osteopontin Gene Variants on Milk Production Traits in Dairy Cattle / S. Leonard, H. Khatib, V. Schutzkus [et al.] // J. Dairy Sci. – 2005. – Vol. 88. – P. 4083-4086.

Poole, D. H. Expression and regulation of secreted phosphoprotein 1 in the bovine corpus luteum and effects on T lymphocyte chemotaxis / D. H. Poole, K. Ndiaye, J. L. Pate // Reproduction. – 2013. – V. 146(6). – P. 527-537. – DOI: 10.1530/REP-13-0190.

Published

2026-08-07

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