FEATURES OF IMMUNOREACTIVITY OF BLV-INFECTED COWS

Authors

  • Maslennikov N.N. FSBEI HE "Kazan State Academy of Veterinary Medicine named after N.E. Bauman"
  • Usoltsev K.V. FSBSI "Federal Centre for Toxicological, Radiation and Biological Safety"
  • Shangaraev R.I. FSBSI "Federal Centre for Toxicological, Radiation and Biological Safety"
  • Zinnatov F.F. FSBEI HE "Kazan State Academy of Veterinary Medicine named after N.E. Bauman"
  • Yakupov T.R. FSBEI HE "Kazan State Academy of Veterinary Medicine named after N.E. Bauman"

Keywords:

leukemia, antibodies, ELISA, PCR, VLCRS, mycobacteria

Abstract

The article the results of a study of blood serum using ELISA and PCR in order to study the characteristics of the immunoreactivity of BLV infected cows described. PCR results confirm the absence of mycobacterial genetic material in the samples, however, all ELISA tests for the detection of mycobacterial antibodies showed positive results. The presented research results allow us to conclude both about the possible determinant commonality of VLBRS and mycobacteria antigens, and about changes in the immunoreactivity of the body of cows infected with BLV.

Author Biographies

Maslennikov N.N., FSBEI HE "Kazan State Academy of Veterinary Medicine named after N.E. Bauman"

Postgraduate student

Usoltsev K.V., FSBSI "Federal Centre for Toxicological, Radiation and Biological Safety"

Candidate of Veterinary Sciences, Leading Researcher

Shangaraev R.I., FSBSI "Federal Centre for Toxicological, Radiation and Biological Safety"

Candidate of Veterinary Sciences, Researcher

Zinnatov F.F., FSBEI HE "Kazan State Academy of Veterinary Medicine named after N.E. Bauman"

Candidate of Biological Sciences, Associate Professor

Yakupov T.R., FSBEI HE "Kazan State Academy of Veterinary Medicine named after N.E. Bauman"

Doctor of Veterinary Sciences, Associate Professor

References

Иванов, О. В. Качество серологической диагностики -- гарантия оздоровления стада от лейкоза крупного рогатого скота / О. В. Иванов, О. Ю. Иванова // Farm Animals. -- 2014. -- № 3. -- С. 26-29.

Магер, С. Н. Биологическая характеристика потомства здоровых и больных лейкозом коров, и ассоциативное развитие лейкоза и туберкулеза у животных / С. Н. Магер // Автореферат диссертации на соискание д.б.н., Новосибирск, 2006.

Сорокина, А. И. Изучение влияния инфицированности вирусом лейкоза и гельминтозов на проявление аллергических туберкулиновых реакций у крупного рогатого скота / А. И. Сорокина // Автореферат диссертации на соискание кандидата ветеринарных наук, Благовещенск, 2000.

Якупов, Т. Р. Молекулярно-генетические и иммунохимические методы в диагностике, индикации и идентификации возбудителей туберкулеза и лейкоза крупного рогатого скота / Т. Р. Якупов // Автореферат дисс. д.вет.н. -- Казань, 2011. -- 49 с.

Якупов, Т. Р. Новые подходы в диагностике лейкоза крупного рогатого скота / Т. Р. Якупов // Ученые записки Казанской государственной академии ветеринарной медицины им. Н.Э. Баумана. -- 2010. -- Т. 204. -- С. 342-347.

Alok C. Characterization of the Antigenic Heterogeneity of Lipoarabinomannan, the Major Surface Glycolipid of Mycobacterium tuberculosis and Complexity of Antibody Specificities toward This Antigen / C. Alok, P. Deendayal, H. William [et all.] // J. Immunol. -- 2018. -- V. 200 (9). -- P. 3053-3066.

Duffy, S. C. Development of a Multiplex Real-Time PCR Assay for Mycobacterium bovis BCG and Validation in a Clinical Laboratory.MicrobiolSpectr / S. C. Duffy, M. Venkatesan, S. Chothe [et all.] // Spectrum.01098-21. Epub. -- 2021. Sep 8.

Ivanov, O. V. Quality of serological diagnostics -- a guarantee of herd health improvement from bovine leukemia / O. V. Ivanov, O. Yu. Ivanova // Farm Animals. -- 2014. -- No. 3. -- P. 26-29.

Mager, S. N. Biological characteristics of offspring of healthy and leukemic cows, and associative development of leukemia and tuberculosis in animals / S. N. Mager // Abstract of dissertation for Doctor of Biological Sciences, Novosibirsk, 2006.

Sorokina, A. I. Study of the influence of leukemia virus infection and helminthiasis on the manifestation of allergic tuberculin reactions in cattle / A. I. Sorokina // Abstract of dissertation for Candidate of Veterinary Sciences, Blagoveshchensk, 2000.

Yakupov, T. R. Molecular-genetic and immunochemical methods in the diagnosis, indication and identification of pathogens of tuberculosis and leukemia of cattle / T. R. Yakupov // Abstract of dissertation for Doctor of Veterinary Sciences. -- Kazan, 2011. -- 49 p.

Yakupov, T. R. New approaches in the diagnosis of bovine leukemia / T. R. Yakupov // Scientific notes of the Kazan State Academy of Veterinary Medicine named after N.E. Bauman. -- 2010. -- Vol. 204. -- P. 342-347.

Alok C. Characterization of the Antigenic Heterogeneity of Lipoarabinomannan, the Major Surface Glycolipid of Mycobacterium tuberculosis and Complexity of Antibody Specificities toward This Antigen / C. Alok, P. Deendayal, H. William [et all.] // J. Immunol. -- 2018. -- V. 200 (9). -- P. 3053-3066.

Duffy, S. C. Development of a Multiplex Real-Time PCR Assay for Mycobacterium bovis BCG and Validation in a Clinical Laboratory.MicrobiolSpectr / S. C. Duffy, M. Venkatesan, S. Chothe [et all.] // Spectrum.01098-21. Epub. -- 2021. Sep 8.

Published

2026-08-12

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