THE EFFECT OF THE PHYTOPREPARATION KARGMEZA ON CELLULAR AND HUMORAL IMMUNITY IN CATTLE PASTEURELLOSIS
УДК: 619:835.2.636.2 DOI: 10.31588/2413_4201_1883_2_254_124
Keywords:
cattle, immunomodulator kargmez, pasteurellosis, T-, B- and NK-lymphocytes, bactericidal and lysozyme activity of blood serumAbstract
The aim of the research was to develop a drug to increase the immunity of animals, as well as to develop a scheme for the etiotropic treatment of pasteurellosis. We found that in animals with pasteurellosis, regardless of breed, there was a suppression of the proliferation of thymus-dependent and bursa-dependent lymphocytes, and an increase in natural killers. A decrease in bactericidal and lysozyme activity of blood serum was established. The effectiveness of the etiotropic treatment of pasteurellosis showed that the number of T- and B-lymphocytes, the level of bactericidal and lysozyme activity of blood serum recovered faster in the Ayrshire and Red-Steppe breeds, which indicated an increase in the immunobiological reactivity of the body compared to the Holstein-Friesian breed.
References
Абушаева, З. Х. Пастереллез крупного рогатого скота / З. Х. Абушаева, Р. А. Абушаев // Инновационные технологии и технические средства для АПК: материалы Международной научно-практической конференции молодых ученых и специалистов (Россия, Воронеж, 12-13 ноября 2020 г.). -- Воронеж. Изд-во Воронежский ГАУ им. Императора Петра I. -- 2020. -- С. 62-65.
Воробьев, В. И. Пастереллез. Этиология, лечение, профилактика у животных в биогеохимических условиях Астраханской области / В. И. Воробьев, Б. Н. Султанов // Сборник научных статей Прикаспийского международного молодежного научного форума агропротехнологий и продовольственной безопасности-2019 (Россия, Астрахань, 23--24 апреля 2019 г). -- Астрахань. -- 2019. -- С. 70-71.
Фараджов, А. Ф. Пастереллез буйволов / А. Ф. Фараджов, Р. Ш. Алиева // Достижения науки и техники АПК. -- 2018. -- Т. 32. -- № 9. -- С. 118.
Benkirane, A. Haemorrhagic septicaemia, its significance, prevention and control in Asia / A. Benkirane, M. C. L. de Alwis // Veterinary Medicine. -- Czech, 2002. -- V. 47. -- N 8. -- P. 234-240.
Berhe, K. Small ruminant pasteurellosis in Tigray region, Ethiopia: Marked serotype diversity may affect vaccine efficacy / K. Berhe, G. Weldeselassie, J. Bettridge // Epidemiol Infect. -- 2017. -- V. 145. -- P. 1326-1338. https://doi.org/10.1017/S095026881600337X.
Gemeda, B. Interventions and tools to improve small ruminant health in Ethiopia / B. Gemeda, H. Desta, K. Roesel // CGIAR. 2016. -- V. 25. -- P. 1-4.
Haji, H. Epidemiology of ovine Pasteurollosis in lume district, east shewa zone of oromiya region, Ethiopia / H. Haji, F. Abunna // Int Know Share Plat. -- 2016. -- V. 6. -- P. 12-20.
Jilo, K. Pasteurellosis Status in Ethiopia: A Comprehensive Review / K. Jilo, T. Belachew, W. Birhanu [et al.] -- DOI: 10.35248/2329-891X.20.8.351 // Journal of Tropical Diseases and Public Health. -- 2020. -- V. 8. -- Iss.4. -- N. 351. -- P. 1-5.
Abushaeva, Z. Kh. Pasteurellosis of cattle / Z. Kh. Abushaeva, R. A. Abushaev // Innovative technologies and technical means for the agro-industrial complex: materials of the International Scientific and Practical Conference of Young Scientists and Specialists (Russia, Voronezh, November 12-13, 2020). -- Voronezh. Publishing house Voronezh State Agrarian University named after Emperor Peter I. -- 2020. -- P. 62-65.
Vorobyov, V. I. Pasteurellosis. Etiology, treatment, prevention in animals in biogeochemical conditions of the Astrakhan region / V. I. Vorobyov, B. N. Sultanov // Collection of scientific articles of the Caspian International Youth Scientific Forum of Agrotechnologies and Food Security-2019 (Russia, Astrakhan, April 23-24, 2019). -- Astrakhan. -- 2019. -- P. 70-71.
Faradzhov, A. F. Pasteurellosis of buffaloes / A. F. Faradzhov, R. Sh. Alieva // Achievements of Science and Technology of the Agro-Industrial Complex. -- 2018. -- Vol. 32. -- No. 9. -- P. 118.
Benkirane, A. Haemorrhagic septicaemia, its significance, prevention and control in Asia / A. Benkirane, M. C. L. de Alwis // Veterinary Medicine. -- Czech, 2002. -- V. 47. -- N 8. -- P. 234-240.
Berhe, K. Small ruminant pasteurellosis in Tigray region, Ethiopia: Marked serotype diversity may affect vaccine efficacy / K. Berhe, G. Weldeselassie, J. Bettridge // Epidemiol Infect. -- 2017. -- V. 145. -- P. 1326-1338. https://doi.org/10.1017/S095026881600337X.
Gemeda, B. Interventions and tools to improve small ruminant health in Ethiopia / B. Gemeda, H. Desta, K. Roesel // CGIAR. 2016. -- V. 25. -- P. 1-4.
Haji, H. Epidemiology of ovine Pasteurollosis in lume district, east shewa zone of oromiya region, Ethiopia / H. Haji, F. Abunna // Int Know Share Plat. -- 2016. -- V. 6. -- P. 12-20.
Jilo, K. Pasteurellosis Status in Ethiopia: A Comprehensive Review / K. Jilo, T. Belachew, W. Birhanu [et al.] -- DOI: 10.35248/2329-891X.20.8.351 // Journal of Tropical Diseases and Public Health. -- 2020. -- V. 8. -- Iss.4. -- N. 351. -- P. 1-5.
