MORPHOFUNCTIONAL FEATURES OF BLOOD PROFILE AND ADAPTIVE POTENTIAL OF CALVES UNDER THE INFLUENCE OF A COMPLEX NANOSTRUCTURED ZEOLITE-BASED PREPARATION
DOI 10.31588/2413_4201_1883_3_267_13 УДК 619:612.11:636.2
Keywords:
calves, nanozeolite, methionine, erythrocytes, hemoglobin, leukocytes, adaptationAbstract
This article examines the dose-dependent effects of a new complex nanostructured preparation based on zeolite and methionine on morphofunctional state of blood and adaptive capacity of young cattle in early ontogenesis. Research and production experiment was carried out in Arsk District of the Republic of Tatarstan on twenty Black-and-White calves aged 20-30 days, divided into four equal groups. Animals in the control group received a basal farm diet, while calves in the experimental groups additionally received the complex preparation at doses of 0.5%, 2.5% and 5% of the feed’s dry matter. Hematological studies were conducted on the 31st day of the experiment using an automatic analyzer. A pronounced nonlinear effect of aluminosilicate complex on blood constants was established. The use of a minimal dose of the preparation of 0.5% ensures the best biostimulating and pronounced anti-stress effects. A significant increase in the red blood cell count to 6.18 × 1012/L and hemoglobin to 102 g/L was recorded. The leukocyte profile of calves in this group showed optimization of the cellular link of nonspecific resistance, expressed in a decrease in the relative pool of segmented neutrophils to 30.33% against a background of an increase in lymphocytes. A significant decrease in the integral index of the neutrophil-to-lymphocyte ratio by 16.1% confirms the minimization of the level of endogenous cortisol stress and optimization of the adaptive potential of young animals. Increasing the sorbent concentration to 5% is accompanied by suppression of erythropoiesis and the total leukocyte pool due to the high cation-exchange load of the supplement in the gastrointestinal tract while maintaining homeostasis constants within the species norm. The use of the preparation at an optimal dose of 0.5% of the dry matter of the diet is physiologically justified.
References
Zeolite and Neurodegenerative Diseases / S. Panaiotov, L. Tancheva, R. Kalfin, P. Petkova-Kirova // Molecules. 2024. Vol. 29. № 11. Р. 2614. https://doi.org/10.3390/molecules29112614.
Pavlak M. S. D., Nunes R. V., Eyng C. Impact of various dietary levels of zeolite on broiler performance, digestibility, and carcass traits // South African Journal of Animal Science. 2022. Vol. 52. № 3. P. 400–408. https://doi.org/10.4314/sajas.v52i3.15.
Zeolite for preventing periparturient hypocalcemia in dairy cows: mechanisms and application strategies / X. Su, P. Huang, Y. Guo, J. Cao // Frontiers in Veterinary Science. 2025. Vol. 12. Art. 1635245. https://doi.org/10.3389/fvets.2025.1635245.
Can Natural and Synthetic Zeolites Be Dietary Modulators of Microorganism Population, Fermentation Parameters, and Methane Emission in the Rumen? A Preliminary Study on Cow / M. P. Majewska, R. Miltko, A. Tuśnio [et al.] // Molecules. 2025. Vol. 30. № 20. Art. 4040. https://doi.org/10.3390/molecules30204040.
Зялалов Ш. Р., Дежаткина С. В., Исайчев В. А. Эффективность производства молока путём введения в рацион коров шарловского диатомита // Вестник Ульяновской государственной сельскохозяйственной академии. 2022. № 2(58). С. 191-196. https://doi.org/ 10.18286/1816-4501-2022-2-191-196.
A meta-analysis of the effects of clay mineral supplementation on alkaline phosphatase, broiler health, and performance / M. M. Sholikin, Sadarman, A. Irawan [et al.] // Poultry Science. 2023. Vol. 102. № 3. Art. 102456. https://doi.org/10.1016/j.psj.2022.102456.
Влияние дегидратированного и обогащённого аминокислотами диатомита на гомеостаз и метаболизм у подсвинков / С. В. Дежаткина, М. Е. Дежаткин, П. В. Зирук [и др.] // Международный вестник ветеринарии. 2025. № 3. С. 311-322. https://doi.org/10.52419/issn2072-2419.2025.3.311.
Effects of zinc-reinforced clinoptilolite on hematological parameters, IgG levels, and enzyme histochemistry in fattening lambs / İ. Kısadere, M. Zengin, Ö. Demirbaş, M. F. Aydın // Turkish Journal of Veterinary & Animal Sciences. 2026. Vol. 50. № 1. P. 8–17. https://doi.org/ 10.55730/1300-0128.4404.
Биологический эффект комплексной кормовой добавки на статус крови и продуктивность дойных коров / А. Т. Варакин, В. В. Саломатин, Г. А. Симонов [и др.] // Известия Нижневолжского агроуниверситетского комплекса: Наука и высшее профессиональное образование. 2023. № 3(71). С. 250-259. https://doi.org/10.32786/2071-9485-2023-03-25.
Bentonite does not affect in vitro ruminal gross fermentations but could modify ruminal metabolome and mineral content. A proof of concept / A. Damato, P. Vanzani, D. Giannuzzi [et al.] // Research in Veterinary Science. 2022. Vol. 144. P. 78–81. https://doi.org/10.1016/j.rvsc.2022.01.012.
The effect of new immunostimulants of tissue and plant origin on the morphological characteristics of the immune system’s central organs and the dynamics of serum immunoglobulins / G. V. Bazekin, E. N. Skorodin, I. F. Dolinin [et al.] // Advances in Animal and Veterinary Sciences. 2021. Vol. 9. № 11. P. 1800–1809. https://doi.org/ 10.17582/journal.aavs/2021/9.11.1800.1809.
